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KFA-115 by Novartis for Melanoma: Likelihood of Approval

Pharmaceutical Technology

According to GlobalData, Phase I drugs for Melanoma have a 76% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how KFA-115’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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KFA-115 by Novartis for Malignant Mesothelioma: Likelihood of Approval

Pharmaceutical Technology

According to GlobalData, Phase I drugs for Malignant Mesothelioma have a 77% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how KFA-115’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks.

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Iptacopan hydrochloride by Novartis for Paroxysmal Nocturnal Hemoglobinuria: Likelihood of Approval

Pharmaceutical Technology

According to GlobalData, Phase III drugs for Paroxysmal Nocturnal Hemoglobinuria have a 60% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. The company offers generic medicines and biosimilars through Sandoz. Buy the report here.

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Iptacopan hydrochloride by Novartis for Glomerulonephritis: Likelihood of Approval

Pharmaceutical Technology

According to GlobalData, Phase III drugs for Glomerulonephritis have a 67% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. GlobalData’s report assesses how Iptacopan hydrochloride’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks.

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Risk adjusted net present value: What is the current valuation of Novartis’s Gevokizumab?

Pharmaceutical Technology

According to Globaldata, it is involved in 34 clinical trials, of which 20 were completed, 1 is ongoing, and 13 were terminated. GlobalData uses proprietary data and analytics to provide a complete picture of Gevokizumab’s valuation in its risk-adjusted NPV model (rNPV). It is a new molecular entity (NME).

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Medicines adherence: Overcoming pharma’s biggest barrier to treatment success

Pharmaceutical Technology

Adherence to medications – defined as the extent to which patients take medications as prescribed by their healthcare providers – can be a significant clinical challenge. The American Medical Association (AMA) lists additional factors [5] such as fear of potential side effects, the cost of prescriptions and a lack of symptoms as significant.

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Why aren’t digital pills taking off?

Pharmaceutical Technology

There’s no dearth of interest, however, in applying digital solutions to healthcare. Jose Castillo-Mancilla, associate professor, School of Medicine, University of Colorado, Anschutz. The digital pill, now marketed by Otsuka Pharmaceuticals, is forecasted to make $27 million in sales in 2022, as per GlobalData.